Statin adjunctive therapy shortens the duration of TB treatment in mice.

Journal:
The Journal of antimicrobial chemotherapy, Volume: 71, Issue: 6
Published:
June 21, 2016
PMID:
26903278
Authors:
Noton K Dutta NK, Natalie Bruiners N, Michael L Pinn ML, Matthew D Zimmerman MD, Brendan Prideaux B, VĂ©ronique Dartois V, Maria L Gennaro ML, Petros C Karakousis PC
Abstract:

The repurposing of existing agents may accelerate TB drug development. Recently, we reported that the lipid-lowering drug simvastatin, when added to the first-line antitubercular regimen, reduces the lung bacillary burden in chronically infected mice.