Renewing the Fight Against TB with an Old Vaccine.

Journal:
Cell, Volume: 180, Issue: 5
Published:
March 5, 2020
PMID:
32142676
Authors:
Thomas J Scriba TJ, Valerie Mizrahi V
Abstract:

Prevention of pulmonary tuberculosis by vaccination has proven an elusive goal. In a recent study, Darrah et al. show that prevention of infection and disease can be achieved in non-human primates by intravenous administration of the century-old vaccine BCG. This finding heralds a step-change in the approach to TB vaccine development.