Renewing the Fight Against TB with an Old Vaccine.

Journal:

Cell, Volume: 180, Issue: 5

Published:

March 5, 2020

PMID:

32142676

Authors:

Thomas J Scriba TJ, Valerie Mizrahi V

Access Paper

DOI: 10.1016/j.cell.2020.02.024

PMID: 32142676

Abstract:

Prevention of pulmonary tuberculosis by vaccination has proven an elusive goal. In a recent study, Darrah et al. show that prevention of infection and disease can be achieved in non-human primates by intravenous administration of the century-old vaccine BCG. This finding heralds a step-change in the approach to TB vaccine development.

Courtesy of the U.S. National Library of Medicine