Drug concentration at the site of disease in children with pulmonary tuberculosis.
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Journal:The Journal of antimicrobial chemotherapy, Volume: 77, Issue: 6
Current TB treatment for children is not optimized to provide adequate drug levels in TB lesions. Dose optimization of first-line antituberculosis drugs to increase exposure at the site of disease could facilitate more optimal treatment and future treatment-shortening strategies across the disease spectrum in children with pulmonary TB.