Publications

Statin adjunctive therapy shortens the duration of TB treatment in mice.

Journal:
The Journal of antimicrobial chemotherapy, Volume: 71, Issue: 6
Published:
June 21, 2016
PMID:
26903278
Authors:
Noton K Dutta NK, Natalie Bruiners N, Michael L Pinn ML, Matthew D Zimmerman MD, Brendan Prideaux B, Véronique Dartois V, Maria L Gennaro ML, Petros C Karakousis PC
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Abstract:

The repurposing of existing agents may accelerate TB drug development. Recently, we reported that the lipid-lowering drug simvastatin, when added to the first-line antitubercular regimen, reduces the lung bacillary burden in chronically infected mice.

Courtesy of the U.S. National Library of Medicine