Decreased plasma rifapentine concentrations associated with AADAC single nucleotide polymorphism in adults with tuberculosis.

Journal:

The Journal of antimicrobial chemotherapy, Volume: 76, Issue: 3

Published:

February 11, 2021

PMID:

33374006

Authors:

Marc Weiner M, Jon Gelfond J, Teresa L Johnson-Pais TL, Melissa Engle M, John L Johnson JL, William C Whitworth WC, Erin Bliven-Sizemore E, Pheona Nsubuga P, Susan E Dorman SE, Rada Savic R,

Access Paper

DOI: 10.1093/jac/dkaa490

PMID: 33374006

Abstract:

Rifapentine exposure is associated with bactericidal activity against Mycobacterium tuberculosis, but high interindividual variation in plasma concentrations is encountered.

Courtesy of the U.S. National Library of Medicine